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A new software and hardware toolkit called SustainaPrint can help users strategically combine strong and weak filaments to achieve the best of both worlds. Instead of printing an entire object with high-performance plastic, the system analyzes a model, predicts where the object is most likely to experience stress, and reinforces those zones with stronger material (Credits: Alex Shipps/MIT CSAIL, using assets from Pixabay and the researchers).
CSAIL article

3D printing has come a long way since its invention in 1983 by Chuck Hull, who pioneered stereolithography, a technique that solidifies liquid resin into solid objects using ultraviolet lasers. Over the decades, 3D printers have evolved from experimental curiosities into tools capable of producing everything from custom prosthetics to complex food designs, architectural models, and even functioning human organs. 

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A brain, a DNA strand, and binary code shine across a bluish, glowing background (Credit: Adobe Stock).
CSAIL article

Most people recognize Alzheimer’s from its devastating symptoms such as memory loss, while new drugs target pathological aspects of disease manifestations, such as plaques of amyloid proteins. Now a sweeping new study in the Sept. 4 edition of Cell by MIT researchers shows the importance of understanding the disease as a battle over how well brain cells control the expression of their genes..  The study paints a high-resolution picture of a desperate struggle to maintain healthy gene expression and gene regulation where the consequences of failure or success are nothing less than the loss or preservation of cell function and cognition.

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"VaxSeer" can predict dominant flu strains and identify the most protective vaccine candidates. The tool uses deep learning models trained on decades of viral sequences and lab test results to simulate how the flu virus might evolve and how the vaccines will respond (Image: Alex Gagne).
CSAIL article

Every year, global health experts are faced with a high-stakes decision: which flu strains should go into the next seasonal vaccine? The choice must be made months in advance, long before flu season even begins, and it can often feel like a race against the clock. If the selected strains match those that circulate, the vaccine will likely be highly effective. But if the prediction is off, protection can drop significantly, leading to (potentially preventable) illness and strain on healthcare systems.