When you’re trying to understand which diseases or physical traits you’re predisposed to, the answers are sprinkled across your DNA. One powerful method for decoding this genetic forecast is polygenic scores, which give patients estimates of their risk for a condition and the likelihood of having physical characteristics (phenotypes, like being tall). Researchers seek to improve the accuracy of these cumulative predictions to account for most of the known genetic contributions.

Your heart is a tireless organ that beats about 3 billion times over an average lifetime and is simply essential for life. Unsurprisingly, cardiovascular disease is the leading cause of death worldwide, costing millions of lives each year. This relentless condition primarily damages the heart, which is divided into four main chambers: the right atrium, left atrium, right ventricle, and left ventricle. Understanding the functions and vulnerabilities of these chambers is crucial in the fight against heart disease.

“I'll have you eating out of the palm of my hand” is an unlikely utterance you'll hear from a robot. Why? Most of them don't have palms.

Imagine a slime-like robot that can seamlessly change its shape to squeeze through narrow spaces, which could be deployed inside the human body to remove an unwanted item.

MIT researchers find circadian variations in liver function play an important role in how drugs are broken down in the body.

For nearly a decade, a team of MIT Computer Science and Artificial Intelligence Laboratory (CSAIL) researchers have been seeking to uncover why certain images persist in a people's minds, while many others fade. To do this, they set out to map the spatio-temporal brain dynamics involved in recognizing a visual image. And now for the first time, scientists harnessed the combined strengths of magnetoencephalography (MEG), which captures the timing of brain activity, and functional magnetic resonance imaging (fMRI), which identifies active brain regions, to precisely determine when and where the brain processes a memorable image.

In biomedicine, segmentation involves annotating pixels from an important structure in a medical image, like an organ or cell. Artificial intelligence models can help clinicians by highlighting pixels that may show signs of a certain disease or anomaly.

To engineer proteins with useful functions, researchers usually begin with a natural protein that has a desirable function, such as emitting fluorescent light, and put it through many rounds of random mutation that eventually generate an optimized version of the protein.

On the surface, the movement disorder amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, and the cognitive disorder frontotemporal lobar degeneration (FTLD), which underlies frontotemporal dementia, manifest in very different ways. In addition, they are known to primarily affect very different regions of the brain.

Imagine yourself glancing at a busy street for a few moments, then trying to sketch the scene you saw from memory. Most people could draw the rough positions of the major objects like cars, people, and crosswalks, but almost no one can draw every detail with pixel-perfect accuracy. The same is true for most modern computer vision algorithms: They are fantastic at capturing high-level details of a scene, but they lose fine-grained details as they process information.