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An analysis of human brain samples ooking for factors associated with neural vulnerability and cognitive resilience amid Alzheimer's disease (Credit: Tsai Lab/The Picower Institute).
CSAIL article

An MIT study published today in Nature provides new evidence for how specific cells and circuits become vulnerable in Alzheimer’s disease, and hones in on other factors that may help some people show resilience to cognitive decline, even amid clear signs of disease pathology. To highlight potential targets for interventions to sustain cognition and memory, the authors engaged in a novel comparison of gene expression across multiple brain regions in people with or without Alzheimer’s disease, and conducted lab experiments to test and validate their major findings.

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alt="The automated, multimodal approach developed by MIT researchers interprets artificial vision models that evaluate the properties of images (Credits: iStock)."
CSAIL article

As artificial intelligence models become increasingly prevalent and are integrated into diverse sectors like health care, finance, education, transportation, and entertainment, understanding how they work under the hood is critical. Interpreting the mechanisms underlying AI models enables us to audit them for safety and biases, with the potential to deepen our understanding of the science behind intelligence itself.